Publications

Integrated cell type-specific analysis of blood and gut identifies matching eQTL for 140 IND risk loc and entrectinib as possible repurposing candidate. Perée H, Petrov VA, Tokunaga Y, Kvasz A, Vieujean S, Regimont S, Mni M, Wéry M, Azarzar S, Jacques S, Fouillien N, Karim L, Deckers M, Detry E, Mayer A, Stephan R, Harshman K, Mizoro Y, Reenaers C, Van Kemseke C, Warling O, Labille V, Kropp S, Poncin M, Moreau AC, Servais B, Loly J-P, SYSCID consortium, BRIDGE consortium, Coppieters W, Dermitzakis E, Louis E, Georges M, Takeda H, Rahmouni S. Submitted.

A systems immunology approach reveals distinct roles of genetic and non-genetic factors in shaping variation of immune responses in cattle. Li S, Myster F, Tang L, Javaux J, Sandor R, Costa Moreira G, Gualdron Duarte JL, Crepin P, Dive M, Mayeres P, Druet T, Netea M, Georges M, Charliert C, Gillet L. Submitted for publication.

Evaluation of genomic selection models using whole genome sequence data and functional annotation in Belgian Blue cattle.  Can Yuan, Alain Gillon, José Luis Gualdrón Duarte, Haruko Takeda, Wouter Coppieters, Michel Georges and Tom Druet. Genet Sel Evol , submitted.

A genome-wide association study in 10,000 individuals links plasma N-glycome to liver disease and anti-inflammatory proteins. Sodbo Sharapov¹, Anna Timoshchuk¹, Olga Zaytseva², Denis Maslov¹, Anna Soplenkova¹, Elizaveta E. Elgaeva^3,4, Evgeny S. Tiys³, Massimo Mangino^5,6, Clemens Wittenbecher⁷, Lennart Karssen⁸, Maria Timofeeva^9,10, Arina Nostaeva^3,8, Frano Vuckovic², Irena Trbojević-Akmačić², Sofya Feoktistova¹¹, Nadezhda A. Potapova^12,13, Viktoria Voroshilova^14,15, Frances Williams⁵ , Dragan Primorac¹⁶, Jan Van Zundert^17,18, Michel Georges¹⁹, Karsten Suhre²⁰, Massimo Allegri²¹, Nishi Chaturvedi²², Malcolm Dunlop⁹, Matthias B. Schulze^23,24,25, Tim Spector⁵, Yakov A. Tsepilov^3,26, Gordan Lauc², Yurii S. Aulchenko^1,3. medRxiv 2024.07.08.24309967; doi: https://doi.org/10.1101/2024.07.08.24309967.

 

Viral clonality signatures identify HTLV-1 asymptomatic carriers at high risk of progression to aggressive leukemia. S Dilip Karpe, M Artesi, J Wayet, K Durkin, V Hahaut, K Uchimaru, J Makiyama, M Iwanaga, A Utsunomiya, K Heezen, A Langerak, A Burny, T Watanabe, M Georges, A Van den Broeke. Submitted.

Identification of an active Helitron transposon family and its role in genome evolution. Peng H, Tang L, Hrunyk N, Kellenberger R, Fossati D, Rimbert H, Sourdille P, Hickmann AB, Ddya F, Charlier C, Choulet F, Bucher E. Submitted.

Lack of evidence supporting transgenerational effects of non-transmitted paternal alleles on the murine transcriptome. Gularte Merida R, Charlier C, Georges M. eLife, in press.

 

A genome-wide association study for survival from a multi-centre European study identified variants associated with COVID-19 risk of death. Minnai F, Biscarini F, Esposito M, Dragani TA, Bujanda L, Rahmouni S, Alarcón-Riquelme ME, Bernardo D, Carnero-Montoro E, Buti M, Zeberg H, Asselta R, Romero-Gómez M; GEN-COVID Multicenter Study; Fernandez-Cadenas I, Fallerini C, Zguro K, Croci S, Baldassarri M, Bruttini M, Furini S, Renieri A, Colombo F.  Sci rep 14:3000 (2024).